Evaluation of Plantago major aqueous extract in treatment of acute urticaria, 2014

Abstract

Urticaria is one of the most common skin disorders that can markedly affect on patients’ quality of life that is associated with
multi strategy management in almost every case. The most important therapeutic method for urticaria is use of antihistamines
such as cetirizine. This method has various side effects such as renal and hepatic complications. The best alternative for this
method is use of traditional medicine and medicinal plants. In this way, Plantago major has been named in several references
of Persian traditional medicine with effective properties in ameliorating urticarial symptoms. Thus, in this double-blind
randomized clinical trial, 48 patients with urticarial were selected and divided into 2 groups, one group was treated with
aqueous extract of Plantago major and another group with cetirizine syrup. According to data of this study, patients who
treated with aqueous extract of Plantago major in comparison with another group, showed a better response to treatment. The
rate of recovery was also higher in patients treated with aqueous extract of Plantago major with no side effects than cetirizine
syrup group. In comparison with cetirizine syrup group, patients treated by extract of Plantago major had a better impact on
patients’ satisfaction. According to results of this study, Plantago extract could be applied for treatment of patients with
.urticaria with no side effects and duration of treatment